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Peter J. Reiser, Ph.D.
Professor
The Ohio State University Medical Center
Department of Oral Biology
4165 Postle Hall
305 West 12th Avenue
Columbus OH 43210
Office Phone: (614) 292-8476
Lab Phone: (614) 247-7335
Email:
reiser.17@osu.edu
Education & Training:
Case Western Reserve University, 1983 American Heart Association
Postdoctoral Fellow
University of Wisconsin, Madison, 1986 National
Institutes of Health Postdoctoral Fellow
Research Interest:
My research is focused on the roles of sarcomeric protein isoforms
in regulating contractile properties of muscle. Specific areas of interest
include craniofacial (extraocular, jaw-closing and laryngeal) muscles,
limb skeletal muscles and cardiac muscle, with an emphasis on comparative
muscle physiology and biochemistry. The approach is based primarily on
analyses of contractile properties and protein composition of single, isolated
muscle cells.
Selected Publications:
- Bicer, S. and P.J. Reiser (2004). Myosin light chain isoform expression
among single mammalian skeletal muscle fibers: species variations.
J. Muscle Res. Cell Motil., 25:623-633.
- Bergrin, M., S. Bicer, C.A. Lucas and P.J. Reiser (2006). Three-dimensional
compartmentalization of myosin heavy chain and light chain isoforms
within dog thyroarytenoid muscle. Am. J. Physiol., 290:C1446-C1458.
- Reiser, P.J. and S. Bicer (2006). Multiple isoforms of myosin light
chain 1 in pig diaphragm slow fibers: correlation with maximal shortening
velocity and force generation. Arch. Biochem. Biophys., 456:112-118.
- Bicer, S. and P.J. Reiser (2007). Variations in apparent mass of
mammalian fast-type myosin light chains correlate with species body
size, from shrew to elephant. Am. J. Physiol., 292:R527 - R534.
- Babu, G.J., P. Bhupathy, V. Timofeyev, N.N. Petrashevskaya, P.J Reiser,
N. Chiamvimonvat and M. Periasamy (2007). Ablation of sarcolipin enhances
sarcoplasmic reticulum calcium transport and atrial contractility.
Proc. Nat. Acad. Sci. (USA), 104:17867-17872.
- Bicer, S., P.J. Reiser, S. Ching, and N. Quan. (2008). Induction
of muscle weakness by local inflammation: an experimental animal model.
Inflammation Res., in press.
- Reiser, PJ, Bicer, S, Patel, R, An, Y, Chen, Q, Quan, (2010) The Myosin Light Chain 1 Isoform Associated with Masticatory Myosin Heavy Chain in Mammals and Reptiles is Embryonic/atrial MLC1. N. J. Exp. Biol., 213:1633-1642.
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